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Protocol for high-throughput screening of SARS-CoV-2 main protease inhibitors using a robust fluorescence polarization assay
Discovery of efficacious antiviral agents targeting SARS-CoV-2 main protease (Mpro) is of the highest importance to fight against COVID-19. Here, we describe a simple protocol for high-throughput screening of Mpro inhibitors using a robust fluorescence polarization (FP) assay. Candidate Mpro inhibit...
Autores principales: | Zhang, Jing, Yan, Haohao, Yan, Gangan, Liu, Xiaoping, Wang, Yanchang, Chen, Yunyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527224/ https://www.ncbi.nlm.nih.gov/pubmed/36317181 http://dx.doi.org/10.1016/j.xpro.2022.101794 |
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