Cargando…

XPF activates break-induced telomere synthesis

Alternative Lengthening of Telomeres (ALT) utilizes a recombination mechanism and break-induced DNA synthesis to maintain telomere length without telomerase, but it is unclear how cells initiate ALT. TERRA, telomeric repeat-containing RNA, forms RNA:DNA hybrids (R-loops) at ALT telomeres. We show th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guh, Chia-Yu, Shen, Hong-Jhih, Chen, Liv WeiChien, Chiu, Pei-Chen, Liao, I-Hsin, Lo, Chen-Chia, Chen, Yunfei, Hsieh, Yu-Hung, Chang, Ting-Chia, Yen, Chien-Ping, Chen, Yi-Yun, Chen, Tom Wei-Wu, Chen, Liuh-Yow, Wu, Ching-Shyi, Egly, Jean-Marc, Chu, Hsueh-Ping Catherine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527253/ https://www.ncbi.nlm.nih.gov/pubmed/36184605 http://dx.doi.org/10.1038/s41467-022-33428-0

Ejemplares similares

Molecular basis of telomere syndrome caused by CTC1 mutations
por: Chen, Liuh-Yow, et al.
Publicado: (2013)

Telomere maintenance during anterior regeneration and aging in the freshwater annelid Aeolosoma viride
por: Chen, Chi-Fan, et al.
Publicado: (2018)

Functions and properties of nuclear lncRNAs—from systematically mapping the interactomes of lncRNAs
por: Guh, Chia-Yu, et al.
Publicado: (2020)

Acetylation of XPF by TIP60 facilitates XPF-ERCC1 complex assembly and activation
por: Wang, Jiajia, et al.
Publicado: (2020)

Profile of the Change in Depression during Proton-Pump Inhibitor Therapy in Patients with Gastroesophageal Reflux Disease: Influence of the Mucosal Break
por: Wu, Chia-Liang, et al.
Publicado: (2021)

FANCM suppresses DNA replication stress at ALT telomeres by disrupting TERRA R-loops
por: Pan, Xiaolei, et al.
Publicado: (2019)

Aspirin Breaks the Crosstalk between 3T3-L1 Adipocytes and 4T1 Breast Cancer Cells by Regulating Cytokine Production
por: Hsieh, Chia-Chien, et al.
Publicado: (2016)

Shear Stress Induces Differentiation of Endothelial Lineage Cells to Protect Neonatal Brain from Hypoxic-Ischemic Injury through NRP1 and VEGFR2 Signaling
por: Huang, Chia-Wei, et al.
Publicado: (2015)

Potential predictors for health-related quality of life in stroke patients undergoing inpatient rehabilitation
por: Chen, Chien-Min, et al.
Publicado: (2015)

ERCC1/XPF Is Important for Repair of DNA Double-Strand Breaks Containing Secondary Structures
por: Li, Shibo, et al.
Publicado: (2019)

Analysis of the associations among Helicobacter pylori infection, adiponectin, leptin, and 10-year fracture risk using the fracture risk assessment tool: A cross-sectional community-based study
por: Chen, Li-Wei, et al.
Publicado: (2017)

ERCC1/XPF Protects Short Telomeres from Homologous Recombination in Arabidopsis thaliana
por: Vannier, Jean-Baptiste, et al.
Publicado: (2009)

The Misconceptions and Determinants of Diabetes Knowledge in Patients with Diabetes in Taiwan
por: Chen, Chia-Chia, et al.
Publicado: (2020)

Mirror Visual Feedback Induces M1 Excitability by Disengaging Functional Connections of Perceptuo-Motor-Attentional Processes during Asynchronous Bimanual Movement: A Magnetoencephalographic Study
por: Lin, Szu-Hung, et al.
Publicado: (2021)

Predictors of In-Hospital Mortality for School-Aged Children with Severe Traumatic Brain Injury
por: Chen, Chih-Chi, et al.
Publicado: (2021)

Complications for a Hoyeraal–Hreidarsson Syndrome Patient with a Germline DKC1 A353V Variant Undergoing Unrelated Peripheral Blood Stem Cell Transplantation
por: Chen, Rong-Long, et al.
Publicado: (2019)

1333. A National Outbreak of Respiratory Syncytial Virus Associated with Emergence of a Genetically Distinct ON1 variant
por: Lin, Wei Hsuan, et al.
Publicado: (2021)

O6-methylguanine-DNA methyltransferase modulates cisplatin-induced DNA double-strand breaks by targeting the homologous recombination pathway in nasopharyngeal carcinoma
por: Chen, Shang-Hung, et al.
Publicado: (2021)

Association between metabolic syndrome and bone fracture risk: A community-based study using a fracture risk assessment tool
por: Yu, Chia-Ying, et al.
Publicado: (2017)

Quantitative Proteomic Analysis of Human Lung Tumor Xenografts Treated with the Ectopic ATP Synthase Inhibitor Citreoviridin
por: Wu, Yi-Hsuan, et al.
Publicado: (2013)

Association of Diabetes and HbA(1c) Levels With Gastrointestinal Manifestations
por: Tseng, Ping-Huei, et al.
Publicado: (2012)

XPF–ERCC1 Blocker Improves the Therapeutic Efficacy of 5-FU- and Oxaliplatin-Based Chemoradiotherapy in Colorectal Cancer
por: Huang, Ming-Yii, et al.
Publicado: (2023)

Effects of stroke on changes in heart rate variability during hemodialysis
por: Huang, Jiun-Chi, et al.
Publicado: (2017)

Simvastatin Sensitizes Radioresistant Prostate Cancer Cells by Compromising DNA Double-Strand Break Repair
por: Chen, Yu-An, et al.
Publicado: (2018)

Association of ERCC1 and XPF polymorphisms with pediatric glioma susceptibility
por: Chen, Yongping, et al.
Publicado: (2023)

Investigating nurses' acceptance of patients’ bring your own device implementation in a clinical setting: A pilot study
por: Chien, Shuo-Chen, et al.
Publicado: (2023)

Expression of Telomeric Repeat–Containing RNA Decreases in Sarcopenia and Increases after Exercise and Nutrition Intervention
por: Chang, Ke-Vin, et al.
Publicado: (2020)

Overexpressed tryptophanyl-tRNA synthetase, an angiostatic protein, enhances oral cancer cell invasiveness
por: Lee, Chien-Wei, et al.
Publicado: (2015)

Effect of medications after cardiac surgery on long-term outcomes in patients with cirrhosis
por: Chou, An-Hsun, et al.
Publicado: (2021)

Supportive Care and Unmet Needs in Upper Gastrointestinal Cancer Patients: Screening and Related Factors
por: Tseng, Ya-Ting, et al.
Publicado: (2021)

Electrophysiological population dynamics reveal context dependencies during decision making in human frontal cortex
por: Shih, Wan-Yu, et al.
Publicado: (2023)

The Symmetry Detection Mechanisms are Color Selective
por: Wu, Chia-Ching, et al.
Publicado: (2014)

The Effect of Size Statistics of the Background Texture on Perceived Target Size
por: Wu, Chia-Ching, et al.
Publicado: (2018)

The Integration of Color-Selective Mechanisms in Symmetry Detection
por: Wu, Chia-Ching, et al.
Publicado: (2017)

Synthesis and Characterization of Thermosensitive P(NIPAAm-co-AAc)-Grafted Silica Nanocomposites for Smart Architectural Coatings
por: Diao, Chien-Chen, et al.
Publicado: (2022)

Recovery of Dysregulated Genes in Cancer-Related Lower Limb Lymphedema After Supermicrosurgical Lymphaticovenous Anastomosis – A Prospective Longitudinal Cohort Study
por: Yang, Johnson Chia-Shen, et al.
Publicado: (2022)

Risk factors of neurological deficit and pulmonary cement embolism after percutaneous vertebroplasty
por: Hsieh, Ming-Kai, et al.
Publicado: (2019)

Case report: right-sided native endocarditis presenting with multiple abscess formations [care compliant]
por: Chan, Tsung-Yu, et al.
Publicado: (2019)

Mineralocorticoid Receptor Antagonists Mitigate Mitral Regurgitation-Induced Myocardial Dysfunction
por: Chang, Wei-Ting, et al.
Publicado: (2022)

CT characteristics and clinical implications of acute type A aortic intramural hematoma
por: Yen, Hsu-Ting, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_kavmra3icfvprhdmmcvrrtan42