Structure of the TnsB transposase-DNA complex of type V-K CRISPR-associated transposon

CRISPR-associated transposons (CASTs) are mobile genetic elements that co-opted CRISPR-Cas systems for RNA-guided transposition. Here we present the 2.4 Å cryo-EM structure of the Scytonema hofmannii (sh) TnsB transposase from Type V-K CAST, bound to the strand transfer DNA. The strand transfer comp...

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Detalles Bibliográficos
Autores principales: Tenjo-Castaño, Francisco, Sofos, Nicholas, López-Méndez, Blanca, Stutzke, Luisa S., Fuglsang, Anders, Stella, Stefano, Montoya, Guillermo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527255/
https://www.ncbi.nlm.nih.gov/pubmed/36184667
http://dx.doi.org/10.1038/s41467-022-33504-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527255/
https://www.ncbi.nlm.nih.gov/pubmed/36184667
http://dx.doi.org/10.1038/s41467-022-33504-5

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