The novel antitumor compound clinopodiside A induces cytotoxicity via autophagy mediated by the signaling of BLK and RasGRP2 in T24 bladder cancer cells

In the study, we investigated the anti-cancer effect of clinopodiside A and the underlying mechanisms using T24 bladder cancer cells as an experimental model. We found that the compound inhibited the growth of the bladder cancer cells in vitro and in vivo in a in a concentration- and dose-dependent...

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Detalles Bibliográficos
Autores principales: Zhou, Rong Sheng, Zhao, Ji Zhong, Guo, Li Ming, Guo, Jia Li, Makawy, Aida El, Li, Zong Yun, Lee, Shao Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527273/
https://www.ncbi.nlm.nih.gov/pubmed/36199691
http://dx.doi.org/10.3389/fphar.2022.982860

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527273/
https://www.ncbi.nlm.nih.gov/pubmed/36199691
http://dx.doi.org/10.3389/fphar.2022.982860

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