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Guanine inhibits the growth of human glioma and melanoma cell lines by interacting with GPR23

Guanine-based purines (GBPs) exert numerous biological effects at the central nervous system through putative membrane receptors, the existence of which is still elusive. To shed light on this question, we screened orphan and poorly characterized G protein-coupled receptors (GPRs), selecting those t...

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Detalles Bibliográficos
Autores principales: Garozzo, Roberta, Zuccarini, Mariachiara, Giuliani, Patricia, Di Liberto, Valentina, Mudò, Giuseppa, Caciagli, Francesco, Ciccarelli, Renata, Ciruela, Francisco, Di Iorio, Patrizia, Condorelli, Daniele F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527276/
https://www.ncbi.nlm.nih.gov/pubmed/36199684
http://dx.doi.org/10.3389/fphar.2022.970891