Expression of vimentin alters cell mechanics, cell-cell adhesion, and gene expression profiles suggesting the induction of a hybrid EMT in human mammary epithelial cells

Vimentin is a Type III intermediate filament (VIF) cytoskeletal protein that regulates the mechanical and migratory behavior of cells. Its expression is considered to be a marker for the epithelial to mesenchymal transition (EMT) that takes place in tumor metastasis. However, the molecular mechanism...

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Detalles Bibliográficos
Autores principales: Sivagurunathan, Suganya, Vahabikashi, Amir, Yang, Haiqian, Zhang, Jun, Vazquez, Kelly, Rajasundaram, Dhivyaa, Politanska, Yuliya, Abdala-Valencia, Hiam, Notbohm, Jacob, Guo, Ming, Adam, Stephen A., Goldman, Robert D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527304/
https://www.ncbi.nlm.nih.gov/pubmed/36200046
http://dx.doi.org/10.3389/fcell.2022.929495

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527304/
https://www.ncbi.nlm.nih.gov/pubmed/36200046
http://dx.doi.org/10.3389/fcell.2022.929495

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