Cargando…

An in vitro assay for enzymatic studies on human ALG13/14 heterodimeric UDP-N-acetylglucosamine transferase

The second step of eukaryotic lipid-linked oligosaccharide (LLO) biosynthesis is catalyzed by the conserved ALG13/ALG14 heterodimeric UDP-N-acetylglucosamine transferase (GnTase). In humans, mutations in ALG13 or ALG14 lead to severe neurological disorders with a multisystem phenotype, known as ALG1...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Chun-Di, Xu, Si, Chen, Shuai, Chen, Zheng-Hui, Dean, Neta, Wang, Ning, Gao, Xiao-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527342/
https://www.ncbi.nlm.nih.gov/pubmed/36200043
http://dx.doi.org/10.3389/fcell.2022.1008078