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An in vitro assay for enzymatic studies on human ALG13/14 heterodimeric UDP-N-acetylglucosamine transferase
The second step of eukaryotic lipid-linked oligosaccharide (LLO) biosynthesis is catalyzed by the conserved ALG13/ALG14 heterodimeric UDP-N-acetylglucosamine transferase (GnTase). In humans, mutations in ALG13 or ALG14 lead to severe neurological disorders with a multisystem phenotype, known as ALG1...
Autores principales: | Wang, Chun-Di, Xu, Si, Chen, Shuai, Chen, Zheng-Hui, Dean, Neta, Wang, Ning, Gao, Xiao-Dong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527342/ https://www.ncbi.nlm.nih.gov/pubmed/36200043 http://dx.doi.org/10.3389/fcell.2022.1008078 |
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