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Polygenic risk score for embryo selection—not ready for prime time

Numerous chronic diseases have a substantial hereditary component. Recent advances in human genetics have allowed the extent of this to be quantified via genome-wide association studies, producing polygenic risk scores (PRS), which can then be applied to individuals to estimate their risk of develop...

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Detalles Bibliográficos
Autores principales: Polyakov, Alex, Amor, David J, Savulescu, Julian, Gyngell, Christopher, Georgiou, Ektoras X, Ross, Vanessa, Mizrachi, Yossi, Rozen, Genia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527452/
https://www.ncbi.nlm.nih.gov/pubmed/35852518
http://dx.doi.org/10.1093/humrep/deac159