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Polygenic risk score for embryo selection—not ready for prime time
Numerous chronic diseases have a substantial hereditary component. Recent advances in human genetics have allowed the extent of this to be quantified via genome-wide association studies, producing polygenic risk scores (PRS), which can then be applied to individuals to estimate their risk of develop...
Autores principales: | Polyakov, Alex, Amor, David J, Savulescu, Julian, Gyngell, Christopher, Georgiou, Ektoras X, Ross, Vanessa, Mizrachi, Yossi, Rozen, Genia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527452/ https://www.ncbi.nlm.nih.gov/pubmed/35852518 http://dx.doi.org/10.1093/humrep/deac159 |
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