Pregabalin Treatment does not Affect Amyloid Pathology in 5XFAD Mice

BACKGROUND: Calcium dysregulation has been proposed to play a causative role in the development of Alzheimer’s disease pathology. Pregabalin is a compound already approved for human use, marketed as the prescription drug Lyrica. It binds the α2-δ subunit of P/Q-type voltage-gated calcium channels, l...

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Detalles Bibliográficos
Autores principales: Sadleir, Katherine R., Popovoic, Jelena, Zhu, Wei, Reidel, Cory T., Do, Ha, Silverman, Richard B., Vassar, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527523/
https://www.ncbi.nlm.nih.gov/pubmed/34259145
http://dx.doi.org/10.2174/1567205018666210713125333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527523/
https://www.ncbi.nlm.nih.gov/pubmed/34259145
http://dx.doi.org/10.2174/1567205018666210713125333

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