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Low Intensity Focused Ultrasound Ignited “Deep-Penetration Nanobomb” (DPNB) for Tetramodal Imaging Guided Hypoxia-Tolerant Sonodynamic Therapy Against Hypoxic Tumors

BACKGROUND: Sonodynamic therapy (SDT) has been regarded as a novel therapeutic modality for killing tumors. However, the hypoxic tumor microenvironment, especially deep-seated tumors distant from blood vessels, severely restricts therapeutic efficacy due to the oxygen-dependent manner of SDT. METHOD...

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Detalles Bibliográficos
Autores principales: Luo, Yuanli, Qiao, Bin, Yang, Chao, Zhang, Ping, Xie, Zhuoyan, Cao, Jin, Yang, Anyu, Xiang, Qinyanqiu, Ran, Haitao, Wang, Zhigang, Hao, Lan, Cao, Yang, Zhou, Zhiyi, Ren, Jianli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527552/
https://www.ncbi.nlm.nih.gov/pubmed/36199475
http://dx.doi.org/10.2147/IJN.S361648