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Mutation of the galectin‐3 glycan‐binding domain ( Lgals3‐R200S) enhances cortical bone expansion in male mice and trabecular bone mass in female mice

We previously observed that genomic loss of galectin‐3 (Gal‐3; encoded by Lgals3) in mice has a significant protective effect on age‐related bone loss. Gal‐3 has both intracellular and extracellular functionality, and we wanted to assess whether the affect we observed in the Lgals3 knockout (KO) mic...

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Detalles Bibliográficos
Autores principales: Maupin, Kevin A., Diegel, Cassandra R., Stevens, Payton D., Dick, Daniel, Williams, Bart O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527582/
https://www.ncbi.nlm.nih.gov/pubmed/36062328
http://dx.doi.org/10.1002/2211-5463.13483