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Palladium-catalyzed/copper-mediated carbon–carbon cross-coupling reaction for synthesis of 6-unsubstituted 2-aryldihydropyrimidines

Dihydropyrimidines (DPs) show a wide range of biological activities for medicinal applications. Among the DP derivatives, 2-aryl-DPs have been reported to display remarkable pharmacological properties. In this work, we describe a method for the synthesis of hitherto unavailable 6-unsubstituted 2-ary...

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Detalles Bibliográficos
Autores principales: Nishimura, Yoshio, Kubo, Takanori, Takayama, Saho, Yoshida, Hanako, Cho, Hidetsura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527642/
https://www.ncbi.nlm.nih.gov/pubmed/36320260
http://dx.doi.org/10.1039/d2ra05155a