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Functional remodelling of perinuclear mitochondria alters nucleoplasmic Ca(2+) signalling in heart failure

Mitochondrial dysfunction in cardiomyocytes is a hallmark of heart failure development. Although initial studies recognized the importance of different mitochondrial subpopulations, there is a striking lack of direct comparison of intrafibrillar (IF) versus perinuclear (PN) mitochondria during the d...

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Detalles Bibliográficos
Autores principales: Voglhuber, Julia, Holzer, Michael, Radulović, Snježana, Thai, Phung N., Djalinac, Natasa, Matzer, Ingrid, Wallner, Markus, Bugger, Heiko, Zirlik, Andreas, Leitinger, Gerd, Dedkova, Elena N., Bers, Donald M., Ljubojevic-Holzer, Senka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527904/
https://www.ncbi.nlm.nih.gov/pubmed/36189813
http://dx.doi.org/10.1098/rstb.2021.0320