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Three-dimensional visualization of the cardiac ryanodine receptor clusters and the molecular-scale fraying of dyads

Clusters of ryanodine receptor calcium channels (RyRs) form the primary molecular machinery of intracellular calcium signalling in cardiomyocytes. While a range of optical super-resolution microscopy techniques have revealed the nanoscale structure of these clusters, the three-dimensional (3D) nanos...

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Detalles Bibliográficos
Autores principales: Sheard, Thomas M. D., Hurley, Miriam E., Smith, Andrew J., Colyer, John, White, Ed, Jayasinghe, Izzy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527906/
https://www.ncbi.nlm.nih.gov/pubmed/36189802
http://dx.doi.org/10.1098/rstb.2021.0316