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Three-dimensional visualization of the cardiac ryanodine receptor clusters and the molecular-scale fraying of dyads
Clusters of ryanodine receptor calcium channels (RyRs) form the primary molecular machinery of intracellular calcium signalling in cardiomyocytes. While a range of optical super-resolution microscopy techniques have revealed the nanoscale structure of these clusters, the three-dimensional (3D) nanos...
Autores principales: | Sheard, Thomas M. D., Hurley, Miriam E., Smith, Andrew J., Colyer, John, White, Ed, Jayasinghe, Izzy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527906/ https://www.ncbi.nlm.nih.gov/pubmed/36189802 http://dx.doi.org/10.1098/rstb.2021.0316 |
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