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Efficacy of neoadjuvant docetaxel + cisplatin chemo-hormonal therapy versus docetaxel chemo-hormonal therapy in patients with locally advanced prostate cancer with germline DNA damage repair gene alterations

PURPOSE: To assess the efficacy and safety of neoadjuvant docetaxel + cisplatin chemotherapy with androgen deprivation therapy for the treatment of locally advanced prostate cancer (PCa) in patients harboring germline DNA damage repair genes (gDDR) defects. METHODS: We conducted a prospective observ...

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Detalles Bibliográficos
Autores principales: Chi, Chenfei, Liu, Jiazhou, Fan, Liancheng, Zhu, Yinjie, Wang, Yanqing, Sha, Jianjun, Huang, Yiran, Dong, Baijun, Pan, Jiahua, Xue, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527989/
https://www.ncbi.nlm.nih.gov/pubmed/36199621
http://dx.doi.org/10.1177/17588359221128356