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Cardiac Myosin Filaments are Maintained by Stochastic Protein Replacement

Myosin and myosin-binding protein C are exquisitely organized into giant filamentous macromolecular complexes within cardiac muscle sarcomeres, yet these proteins must be continually replaced to maintain contractile fidelity. The overall hypothesis that myosin filament structure is dynamic and allow...

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Detalles Bibliográficos
Autores principales: Wood, Neil B., Kelly, Colleen M., O’Leary, Thomas S., Martin, Jody L., Previs, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9528119/
https://www.ncbi.nlm.nih.gov/pubmed/35921914
http://dx.doi.org/10.1016/j.mcpro.2022.100274