GDF11 inhibits adipogenesis and improves mature adipocytes metabolic function via WNT/β‐catenin and ALK5/SMAD2/3 pathways

OBJECTIVE: GDF11 is a member of the TGF‐β superfamily that was recently implicated as potential “rejuvenating” factor, which can ameliorate metabolic disorders. The main objective of the presented study was to closely characterize the role of GDF11 signaling in the glucose homeostasis and in the dif...

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Detalles Bibliográficos
Autores principales: Frohlich, Jan, Kovacovicova, Kristina, Raffaele, Marco, Virglova, Tereza, Cizkova, Eliska, Kucera, Jan, Bienertova‐Vasku, Julie, Wabitsch, Martin, Peyrou, Marion, Bonomini, Francesca, Rezzani, Rita, Chaldakov, George N., Tonchev, Anton B., Di Rosa, Michelino, Blavet, Nicolas, Hejret, Vaclav, Vinciguerra, Manlio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9528760/
https://www.ncbi.nlm.nih.gov/pubmed/35920128
http://dx.doi.org/10.1111/cpr.13310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9528760/
https://www.ncbi.nlm.nih.gov/pubmed/35920128
http://dx.doi.org/10.1111/cpr.13310

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