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TGF‐β1 peptide‐based inhibitor P144 ameliorates renal fibrosis after ischemia–reperfusion injury by modulating alternatively activated macrophages

OBJECTIVES: Ischemia–reperfusion injury (IRI) is a major cause of chronic renal fibrosis. Currently, numerous therapies have shown a minimal effect on the blockade of fibrosis progression. Here, the therapeutic potential of peptide‐based TGF‐β1 inhibitor P144 in IRI‐induced renal fibrosis and the un...

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Detalles Bibliográficos
Autores principales: Li, Delun, Zhang, Jian, Yuan, Siyu, Wang, Chao, Chang, Jiakai, Tong, Yan, Liu, Ran, Sang, Tian, Li, Lili, Li, Jijun, Ouyang, Qing, Chen, Xiangmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9528764/
https://www.ncbi.nlm.nih.gov/pubmed/35762283
http://dx.doi.org/10.1111/cpr.13299