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Pygopus2 ameliorates mesenteric adipocyte poor differentiation to alleviate Crohn's disease ‐like colitis via the Axin2/GSK3β pathway

OBJECTIVES: Crohn's disease (CD) mesenteric adipose tissue (MAT) inflammation affects enteritis through the interaction between the mesentery and intestine, and we previously found that poorly differentiated mesenteric adipocytes were related to its inflammatory features. Pygopus2 (Pygo2) is a...

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Detalles Bibliográficos
Autores principales: Li, Jing, Zuo, Lugen, Geng, Zhijun, Li, Qingqing, Cheng, Yang, Yang, Zi, Shi, Ruohan, Zhou, Yueqing, Nie, Wenhu, Wang, Yueyue, Zhang, Xiaofeng, Ge, Sitang, Song, Xue, Hu, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9528773/
https://www.ncbi.nlm.nih.gov/pubmed/35707871
http://dx.doi.org/10.1111/cpr.13292