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Rapid restructurization of conformationally-distinct alpha-synuclein amyloid fibrils at an elevated temperature

Protein aggregation in the form of amyloid fibrils is linked with the onset and progression of more than 30 amyloidoses, including multiple neurodegenerative disorders, such as Alzheimer’s or Parkinson’s disease. Despite countless studies and years of research, the process of such aggregate formatio...

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Detalles Bibliográficos
Autores principales: Ziaunys, Mantas, Sakalauskas, Andrius, Mikalauskaite, Kamile, Smirnovas, Vytautas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9528901/
https://www.ncbi.nlm.nih.gov/pubmed/36199282
http://dx.doi.org/10.7717/peerj.14137