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Rapid restructurization of conformationally-distinct alpha-synuclein amyloid fibrils at an elevated temperature
Protein aggregation in the form of amyloid fibrils is linked with the onset and progression of more than 30 amyloidoses, including multiple neurodegenerative disorders, such as Alzheimer’s or Parkinson’s disease. Despite countless studies and years of research, the process of such aggregate formatio...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9528901/ https://www.ncbi.nlm.nih.gov/pubmed/36199282 http://dx.doi.org/10.7717/peerj.14137 |