Detection of a GLIS3 fusion in an infant with AML refractory to chemotherapy

Infants diagnosed with acute myeloid leukemia (AML) frequently harbor cytogenetically cryptic fusions involving KMT2A, NUP98, or GLIS2. Those with AML driven specifically by CBFA2T3::GLIS2 fusions have a dismal prognosis and are currently risk-stratified to receive hematopoietic stem cell transplant...

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Detalles Bibliográficos
Autores principales: Smith, Stephen M., Lee, Alex G., Tong, Schuyler, Leung, Stanley G., Hongo, Henry, Rivera, Jose M., Sweet-Cordero, E. Alejandro, Michlitsch, Jennifer, Stieglitz, Elliot
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Rapid Cancer Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9528968/
https://www.ncbi.nlm.nih.gov/pubmed/35927023
http://dx.doi.org/10.1101/mcs.a006220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9528968/
https://www.ncbi.nlm.nih.gov/pubmed/35927023
http://dx.doi.org/10.1101/mcs.a006220

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