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Assembler artifacts include misassembly because of unsafe unitigs and underassembly because of bidirected graphs

Recent assemblies by the T2T and VGP consortia have achieved significant accuracy but required a tremendous amount of effort and resources. More typical assembly efforts, on the other hand, still suffer both from misassemblies (joining sequences that should not be adjacent) and from underassemblies...

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Detalles Bibliográficos
Autores principales: Rahman, Amatur, Medvedev, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9528984/
https://www.ncbi.nlm.nih.gov/pubmed/35896425
http://dx.doi.org/10.1101/gr.276601.122