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Assembler artifacts include misassembly because of unsafe unitigs and underassembly because of bidirected graphs
Recent assemblies by the T2T and VGP consortia have achieved significant accuracy but required a tremendous amount of effort and resources. More typical assembly efforts, on the other hand, still suffer both from misassemblies (joining sequences that should not be adjacent) and from underassemblies...
Autores principales: | Rahman, Amatur, Medvedev, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9528984/ https://www.ncbi.nlm.nih.gov/pubmed/35896425 http://dx.doi.org/10.1101/gr.276601.122 |
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