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Abnormal transcriptome-wide DNA demethylation induced by folate deficiency causes neural tube defects

Neural tube defect (NTDs) is one of the most common and serious fetal and neonatal birth defects. Neural tube closure (NTC) is an exquisitely coordinated process and this procedure is influenced by both genetic and environmental factor. Folic acid (FA) supplementation is an effective for prevention...

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Detalles Bibliográficos
Autores principales: Wang, Shan, Zeng, Yubing, Pei, Pei, He, Xuejia, Liu, Fan, Zhang, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529027/
https://www.ncbi.nlm.nih.gov/pubmed/36199572
http://dx.doi.org/10.3389/fgene.2022.987210