Impact of CYP3A5 Status on the Clinical and Financial Outcomes Among African American Kidney Transplant Recipients

Pharmacogenetic profiling of transplant recipients demonstrates that the marked variation in the metabolism of immunosuppressive medications, particularly tacrolimus, is related to genetic variants. Patients of African ancestry are less likely to carry loss-of-function (LoF) variants in the CYP3A5 g...

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Detalles Bibliográficos
Autores principales: Obayemi, Joy, Keating, Brendan, Callans, Lauren, Lentine, Krista L., Schnitzler, Mark A., Caliskan, Yasar, Xiao, Huiling, Dharnidharka, Vikas R., Mannon, Roslyn B., Axelrod, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Kidney Transplantation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529042/
https://www.ncbi.nlm.nih.gov/pubmed/36204191
http://dx.doi.org/10.1097/TXD.0000000000001379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529042/
https://www.ncbi.nlm.nih.gov/pubmed/36204191
http://dx.doi.org/10.1097/TXD.0000000000001379

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