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SARS-CoV-2 infection drives an inflammatory response in human adipose tissue through infection of adipocytes and macrophages

Obesity, characterized by chronic low-grade inflammation of the adipose tissue, is associated with adverse coronavirus disease 2019 (COVID-19) outcomes, yet the underlying mechanism is unknown. To explore whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection of adipose tissu...

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Detalles Bibliográficos
Autores principales: Martínez-Colón, Giovanny J., Ratnasiri, Kalani, Chen, Heping, Jiang, Sizun, Zanley, Elizabeth, Rustagi, Arjun, Verma, Renu, Chen, Han, Andrews, Jason R., Mertz, Kirsten D., Tzankov, Alexandar, Azagury, Dan, Boyd, Jack, Nolan, Garry P., Schürch, Christian M., Matter, Matthias S., Blish, Catherine A., McLaughlin, Tracey L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529056/
https://www.ncbi.nlm.nih.gov/pubmed/36137009
http://dx.doi.org/10.1126/scitranslmed.abm9151