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A pan-cancer analysis of matrisome proteins reveals CTHRC1 and a related network as major ECM regulators across cancers

The extracellular matrix in the tumour microenvironment can regulate cancer cell growth and progression. A pan-cancer analysis of TCGA data from 30 cancer types, identified the top 5% of matrisome genes with amplifications or deletions in their copy number, that affect their expression and cancer su...

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Detalles Bibliográficos
Autores principales: Harikrishnan, Keerthi, Prabhu, Srinivas Sheshagiri, Balasubramanian, Nagaraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529084/
https://www.ncbi.nlm.nih.gov/pubmed/36190948
http://dx.doi.org/10.1371/journal.pone.0270063