The introduction of mutations in the wild type coxsackievirus B3 (CVB3) IRES RNA leads to different levels of in vitro reduced replicative and translation efficiencies

Coxsackievirus B3 (CVB3) is a principal causative agent of viral myocarditis, meningitis and pancreatitis. There is no vaccine available for clinical use. It has been demonstrated that the primary molecular determinant of virulence phenotype is located in the 5’ UTR of the viral genome. Translation...

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Detalles Bibliográficos
Autores principales: Gharbi, Jawhar, Almalki, Mohammed A., Ben M’hadheb, Manel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529112/
https://www.ncbi.nlm.nih.gov/pubmed/36190999
http://dx.doi.org/10.1371/journal.pone.0274162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529112/
https://www.ncbi.nlm.nih.gov/pubmed/36190999
http://dx.doi.org/10.1371/journal.pone.0274162

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