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Type 1 and Type 2 Epstein-Barr viruses induce proliferation, and inhibit differentiation, in infected telomerase-immortalized normal oral keratinocytes

Differentiated epithelial cells are an important source of infectious EBV virions in human saliva, and latent Epstein-Barr virus (EBV) infection is strongly associated with the epithelial cell tumor, nasopharyngeal carcinoma (NPC). However, it has been difficult to model how EBV contributes to NPC,...

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Detalles Bibliográficos
Autores principales: Singh, Deo R., Nelson, Scott E., Pawelski, Abigail S., Cantres-Velez, Juan A., Kansra, Alisha S., Pauly, Nicholas P., Bristol, Jillian A., Hayes, Mitchell, Ohashi, Makoto, Casco, Alejandro, Lee, Denis, Fogarty, Stuart A., Lambert, Paul F., Johannsen, Eric C., Kenney, Shannon C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529132/
https://www.ncbi.nlm.nih.gov/pubmed/36190982
http://dx.doi.org/10.1371/journal.ppat.1010868