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The germ cell-specific RNA binding protein RBM46 is essential for spermatogonial differentiation in mice

Control over gene expression is exerted, in multiple stages of spermatogenesis, at the post-transcriptional level by RNA binding proteins (RBPs). We identify here an essential role in mammalian spermatogenesis and male fertility for ‘RNA binding protein 46’ (RBM46). A highly evolutionarily conserved...

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Detalles Bibliográficos
Autores principales: Peart, Natoya J., Johnson, Taylor A., Lee, Sungkyoung, Sears, Matthew J., Yang, Fang, Quesnel-Vallières, Mathieu, Feng, Huijuan, Recinos, Yocelyn, Barash, Yoseph, Zhang, Chaolin, Hermann, Brian P., Wang, P. Jeremy, Geyer, Christopher B., Carstens, Russ P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529142/
https://www.ncbi.nlm.nih.gov/pubmed/36129965
http://dx.doi.org/10.1371/journal.pgen.1010416