Pharmacological Inhibition of Chitotriosidase (CHIT1) as a Novel Therapeutic Approach for Sarcoidosis

INTRODUCTION: Sarcoidosis is a systemic disease of unknown etiology characterized by granuloma formation in the affected tissues. The pathologically activated macrophages are causatively implicated in disease pathogenesis and play important role in granuloma formation. Chitotriosidase (CHIT1), macro...

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Detalles Bibliográficos
Autores principales: Dymek, Barbara, Sklepkiewicz, Piotr, Mlacki, Michal, Güner, Nazan Cemre, Nejman-Gryz, Patrycja, Drzewicka, Katarzyna, Przysucha, Natalia, Rymaszewska, Aleksandra, Paplinska-Goryca, Magdalena, Zagozdzon, Agnieszka, Proboszcz, Małgorzata, Krzemiński, Łukasz, von der Thüsen, Jan H, Górska, Katarzyna, Dzwonek, Karolina, Zasłona, Zbigniew, Dobrzanski, Pawel, Krenke, Rafał
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529231/
https://www.ncbi.nlm.nih.gov/pubmed/36199746
http://dx.doi.org/10.2147/JIR.S378357

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529231/
https://www.ncbi.nlm.nih.gov/pubmed/36199746
http://dx.doi.org/10.2147/JIR.S378357

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