S6K1 phosphorylates Cdk1 and MSH6 to regulate DNA repair

The mTORC1 substrate, S6 Kinase 1 (S6K1), is involved in the regulation of cell growth, ribosome biogenesis, glucose homeostasis, and adipogenesis. Accumulating evidence has suggested a role for mTORC1 signaling in the DNA damage response. This is mostly based on the findings that mTORC1 inhibitors...

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Detalles Bibliográficos
Autores principales: Amar-Schwartz, Adi, Ben Hur, Vered, Jbara, Amina, Cohen, Yuval, Barnabas, Georgina D, Arbib, Eliran, Siegfried, Zahava, Mashahreh, Bayan, Hassouna, Fouad, Shilo, Asaf, Abu-Odeh, Mohammad, Berger, Michael, Wiener, Reuven, Aqeilan, Rami, Geiger, Tamar, Karni, Rotem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529248/
https://www.ncbi.nlm.nih.gov/pubmed/36189922
http://dx.doi.org/10.7554/eLife.79128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529248/
https://www.ncbi.nlm.nih.gov/pubmed/36189922
http://dx.doi.org/10.7554/eLife.79128

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