Cargando…

FXYD3 facilitates Na(+) and liquid absorption across human airway epithelia by increasing the transport capacity of the Na/K ATPase

Na/K ATPase activity is essential for ion transport across epithelia. FXYD3, a γ subunit of the Na/K ATPase, is expressed in the airway, but its function remains undetermined. Single-cell RNA sequencing and immunohistochemistry revealed that FXYD3 localizes within the basolateral membrane of all air...

Descripción completa

Detalles Bibliográficos
Autores principales: Cano Portillo, Camilo, Villacreses, Raul, Thurman, Andrew L., Pezzulo, Alejandro A., Zabner, Joseph, Thornell, Ian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529271/
https://www.ncbi.nlm.nih.gov/pubmed/35993520
http://dx.doi.org/10.1152/ajpcell.00047.2022