Cargando…

FXYD3 facilitates Na(+) and liquid absorption across human airway epithelia by increasing the transport capacity of the Na/K ATPase

Na/K ATPase activity is essential for ion transport across epithelia. FXYD3, a γ subunit of the Na/K ATPase, is expressed in the airway, but its function remains undetermined. Single-cell RNA sequencing and immunohistochemistry revealed that FXYD3 localizes within the basolateral membrane of all air...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cano Portillo, Camilo, Villacreses, Raul, Thurman, Andrew L., Pezzulo, Alejandro A., Zabner, Joseph, Thornell, Ian M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Physiological Society 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529271/ https://www.ncbi.nlm.nih.gov/pubmed/35993520 http://dx.doi.org/10.1152/ajpcell.00047.2022

Ejemplares similares

FXYD5: Na(+)/K(+)-ATPase Regulator in Health and Disease
por: Lubarski Gotliv, Irina
Publicado: (2016)

Displacement of Native FXYD Protein From Na(+)/K(+)-ATPase With Novel FXYD Peptide Derivatives: Effects on Doxorubicin Cytotoxicity
por: Liu, Chia-Chi, et al.
Publicado: (2022)

Renal Mg handling, FXYD2 and the central role of the Na,K‐ATPase
por: Mayan, Haim, et al.
Publicado: (2018)

CFTR-rich ionocytes mediate chloride absorption across airway epithelia
por: Lei, Lei, et al.
Publicado: (2023)

FXYD8, a Novel Regulator of Renal Na(+)/K(+)-ATPase in the Euryhaline Teleost, Tetraodon nigroviridis
por: Wang, Pei-Jen, et al.
Publicado: (2017)

Beneficial Renal and Pancreatic Phenotypes in a Mouse Deficient in FXYD2 Regulatory Subunit of Na,K-ATPase
por: Arystarkhova, Elena
Publicado: (2016)

Paracellular bicarbonate flux across human cystic fibrosis airway epithelia tempers changes in airway surface liquid pH
por: Thornell, Ian M., et al.
Publicado: (2020)

FXYD2 and Na,K-ATPase Expression in Isolated Human Proximal Tubular Cells: Disturbed Upregulation on Renal Hypomagnesemia?
por: Cairo, Edinio R., et al.
Publicado: (2009)

Effect of differentiation, de novo innervation, and electrical pulse stimulation on mRNA and protein expression of Na(+),K(+)-ATPase, FXYD1, and FXYD5 in cultured human skeletal muscle cells
por: Jan, Vid, et al.
Publicado: (2021)

Different Modulatory Mechanisms of Renal FXYD12 for Na(+)-K(+)-ATPase between Two Closely Related Medakas upon Salinity Challenge
por: Yang, Wen-Kai, et al.
Publicado: (2016)

FXYD6 Regulates Chemosensitivity by Mediating the Expression of Na+/K+-ATPase α1 and Affecting Cell Autophagy and Apoptosis in Colorectal Cancer
por: Luo, Wen, et al.
Publicado: (2021)

FXYD protein isoforms differentially modulate human Na/K pump function
por: Meyer, Dylan J., et al.
Publicado: (2020)

Paradoxical activation of the sodium chloride cotransporter (NCC) without hypertension in kidney deficient in a regulatory subunit of Na,K‐ATPase, FXYD2
por: Arystarkhova, Elena, et al.
Publicado: (2014)

Regulation of the Na,K-ATPase Gamma-Subunit FXYD2 by Runx1 and Ret Signaling in Normal and Injured Non-Peptidergic Nociceptive Sensory Neurons
por: Ventéo, Stéphanie, et al.
Publicado: (2012)

Vitamin D-mediated effects on airway innate immunity in vitro
por: Stapleton, Emma M., et al.
Publicado: (2022)

Quantitative Chest CT Assessment of Small Airways Disease in Post-Acute SARS-CoV-2 Infection
por: Cho, Josalyn L., et al.
Publicado: (2022)

High-Intensity Training Represses FXYD5 and Glycosylates Na,K-ATPase in Type II Muscle Fibres, Which Are Linked with Improved Muscle K(+) Handling and Performance
por: Hostrup, Morten, et al.
Publicado: (2023)

Membrane Lipid Microenvironment Modulates Thermodynamic Properties of the Na(+)-K(+)-ATPase in Branchial and Intestinal Epithelia in Euryhaline Fish In vivo
por: Díaz, Mario, et al.
Publicado: (2016)

Measles virus exits human airway epithelia within dislodged metabolically active infectious centers
por: Hippee, Camilla E., et al.
Publicado: (2021)

Na(+)/Ca(2+) exchange and Na(+)/K(+)-ATPase in the heart
por: Shattock, Michael J, et al.
Publicado: (2015)

Kinetics of Na-ATPase activity by the Na,K pump. Interactions of the phosphorylated intermediates with Na+, Tris+, and K+
Publicado: (1983)

β subunit affects Na(+) and K(+) affinities of Na(+)/K(+)-ATPase: Na(+) and K(+) affinities of a hybrid Na(+)/K(+)-ATPase composed of insect α and mammalian β subunits
por: Homareda, Haruo, et al.
Publicado: (2022)

Distinguishing roles of the membrane-cytoskeleton and cadherin mediated cell-cell adhesion in generating different Na+,K(+)-ATPase distributions in polarized epithelia
Publicado: (1993)

Endogenous Na(+), K(+)-ATPase inhibitors and CSF [Na(+)] contribute to migraine formation
por: Gross, Noah B., et al.
Publicado: (2019)

Prognostic significance of sodium-potassium ATPase regulator, FXYD3, in human hepatocellular carcinoma
por: Wang, Li-Juan, et al.
Publicado: (2018)

WNK Inhibition Increases Surface Liquid pH and Host Defense in Cystic Fibrosis Airway Epithelia
por: Rehman, Tayyab, et al.
Publicado: (2022)

C-peptide, Na(+),K(+)-ATPase, and Diabetes
por: Vague, P., et al.
Publicado: (2004)

Tuning of the Na,K-ATPase by the beta subunit
por: Hilbers, Florian, et al.
Publicado: (2016)

Transcriptional regulators of Na,K-ATPase subunits
por: Li, Zhiqin, et al.
Publicado: (2015)

Na(+), K(+)-ATPase Signaling and Bipolar Disorder
por: Lichtstein, David, et al.
Publicado: (2018)

Na/K-ATPase and Regulation of Sperm Function
por: Thundathil, Jacob C., et al.
Publicado: (2018)

The role of Na(+)‐K(+)‐ATPase in the epileptic brain
por: Sun, Jinyi, et al.
Publicado: (2022)

Ultrastructure of Na,K-transport vesicles reconstituted with purified renal Na,K-ATPase
Publicado: (1980)

Glutamate Water Gates in the Ion Binding Pocket of Na(+) Bound Na(+), K(+)-ATPase
por: Han, Minwoo, et al.
Publicado: (2017)

(−)-Englerin A-evoked Cytotoxicity Is Mediated by Na(+) Influx and Counteracted by Na(+)/K(+)-ATPase
por: Ludlow, Melanie J., et al.
Publicado: (2017)

Na/K Pump and Beyond: Na/K-ATPase as a Modulator of Apoptosis and Autophagy
por: Felippe Gonçalves-de-Albuquerque, Cassiano, et al.
Publicado: (2017)

Airway Epithelia
por: Johnson, Larry G., et al.
Publicado: (2003)

Na(+)-stimulated ATPase of alkaliphilic halotolerant cyanobacterium Aphanothece halophytica translocates Na(+ )into proteoliposomes via Na(+ )uniport mechanism
por: Soontharapirakkul, Kanteera, et al.
Publicado: (2010)

Isoform-Specific Regulation and Localization of the Coxsackie and Adenovirus Receptor in Human Airway Epithelia
por: Excoffon, Katherine J. D. A., et al.
Publicado: (2010)

Compensatory regulation of Na(+) absorption by Na(+)/H(+) exchanger and Na(+)-Cl(-) cotransporter in zebrafish (Danio rerio)
por: Chang, Wei-Jen, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_nn40bq5i5nionc9i36i5e4k4us