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Dl-3-n-Butylphthalide (NBP) Mitigates Muscular Injury Induced by Limb Ischemia/Reperfusion in Mice through the HMGB1/TLR4/NF-κB Pathway

OBJECTIVE: Limb ischemia/reperfusion (I/R) injury is a clinical syndrome associated with severe damages to skeletal muscles and other fatal outcomes. Oxidative stress and inflammatory response play vital roles in the development of limb I/R injury. Existing evidence further indicates that Dl-3-n-but...

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Detalles Bibliográficos
Autores principales: Sun, Huanhuan, Wang, Jueqiong, Bi, Wei, Zhang, Feng, Chi, Kui, Shi, Long, Li, Meng, Zhang, Jinwen, Zhang, Yanrong, Gao, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529425/
https://www.ncbi.nlm.nih.gov/pubmed/36199552
http://dx.doi.org/10.1155/2022/5556067