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ALK7 Knockdown Plays a Protective Role on HG-Stimulated MCs through Activation of the Nrf2/HO-1 Pathway

OBJECTIVE: Activin receptor-like kinase 7 (ALK7) is a member of the ALK family that has a key role in diabetes. However, the role of ALK7 in diabetic nephropathy (DN) remains unclear. METHODS: Herein, we evaluated the effects of ALK7 on mesangial cells (MCs). MCs were transfected with si-ALK7 or pcD...

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Detalles Bibliográficos
Autores principales: Gao, Shan, Wu, Guifu, Li, Hui, Qiao, Yuan, Dong, Chunping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529459/
https://www.ncbi.nlm.nih.gov/pubmed/36199821
http://dx.doi.org/10.1155/2022/4064733