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Protocol to use TopNet for gene regulatory network modeling using gene expression data from perturbation experiments
Inference of gene regulatory networks from gene perturbation experiments is the most reliable approach for investigating interdependence between genes. Here, we describe the initial gene perturbations, expression measurements, and preparation steps, followed by network modeling using TopNet. Summari...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529586/ https://www.ncbi.nlm.nih.gov/pubmed/36181678 http://dx.doi.org/10.1016/j.xpro.2022.101737 |