Molecular mechanism of UV damage modulation in nucleosomes

Exposure to ultraviolet (UV) light causes the formation of mutagenic cyclobutane pyrimidine dimers (CPDs) in cellular DNA. Previous studies have revealed that CPD formation in nucleosomes, the building blocks of chromatin, shows a striking ∼10 base pair (bp) periodic pattern. CPD formation is suppre...

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Detalles Bibliográficos
Autores principales: Stark, Bastian, Poon, Gregory M.K., Wyrick, John J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529667/
https://www.ncbi.nlm.nih.gov/pubmed/36212527
http://dx.doi.org/10.1016/j.csbj.2022.08.071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529667/
https://www.ncbi.nlm.nih.gov/pubmed/36212527
http://dx.doi.org/10.1016/j.csbj.2022.08.071

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