Bio-behavioural changes in treatment-resistant socially isolated FSL rats show variable or improved response to combined fluoxetine-olanzapine versus olanzapine treatment

BACKGROUND: Exposure of Flinders Sensitive Line (FSL) rats to post-weaning social isolation rearing (SIR) causes depressive- and social anxiety-like symptoms resistant to, or worsened by, fluoxetine. SIR typically presents with psychotic-like symptoms, while the paradoxical response to fluoxetine su...

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Detalles Bibliográficos
Autores principales: Mncube, K., Harvey, B.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529672/
https://www.ncbi.nlm.nih.gov/pubmed/36204253
http://dx.doi.org/10.1016/j.ibneur.2022.08.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529672/
https://www.ncbi.nlm.nih.gov/pubmed/36204253
http://dx.doi.org/10.1016/j.ibneur.2022.08.009

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