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Protein engineering for feedback resistance in 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase

ABSTRACT: The shikimate pathway delivers aromatic amino acids (AAAs) in prokaryotes, fungi, and plants and is highly utilized in the industrial synthesis of bioactive compounds. Carbon flow into this pathway is controlled by the initial enzyme 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (DA...

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Detalles Bibliográficos
Autores principales: Jayaraman, Kumaresan, Trachtmann, Natalia, Sprenger, Georg A., Gohlke, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529685/
https://www.ncbi.nlm.nih.gov/pubmed/36109385
http://dx.doi.org/10.1007/s00253-022-12166-9