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MiR-205 Regulates LRRK2 Expression in Dopamine Neurons in Parkinson’s Disease through Methylation Modification

BACKGROUND: We explored the methylation modification in miR-205 promoter during the pathological changes of Parkinson’s disease (PD) and its regulation on Leucine-Rich Repeat Kinase 2 (LRRK2), clarified the important role of methylation in miR-205 promoter region in PD, explained the role of miR-205...

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Detalles Bibliográficos
Autores principales: Wang, Hongwei, Li, Jie, Tao, Liang, Lv, Luting, Sun, Jinghui, Zhang, Tengteng, Wang, Huimin, Wang, Jiandong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529724/
https://www.ncbi.nlm.nih.gov/pubmed/36248294
http://dx.doi.org/10.18502/ijph.v51i7.10098