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Clinical and Molecular Validation of BAP1, MTAP, P53, and Merlin Immunohistochemistry in Diagnosis of Pleural Mesothelioma

BAP1 and MTAP immunostains play an important role in diagnosis of mesothelioma, but additional markers are needed to increase sensitivity. We analyzed 84 pleural mesotheliomas (51 epithelioid, 27 biphasic, 6 sarcomatoid) by a hybrid-capture next-generation sequencing (NGS) panel including complete c...

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Detalles Bibliográficos
Autores principales: Chapel, David B., Hornick, Jason L., Barlow, Julianne, Bueno, Raphael, Sholl, Lynette M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529776/
https://www.ncbi.nlm.nih.gov/pubmed/35459788
http://dx.doi.org/10.1038/s41379-022-01081-z