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Diesel exhaust particles induce human umbilical vein endothelial cells apoptosis by accumulation of autophagosomes and caspase-8 activation

Diesel exhaust particles (DEP) are risk factors for endothelial cells (ECs) dysfunction. However, the mechanism by which DEP induce ECs apoptosis remains unclear. Here, we investigated how DEP induce death of human umbilical vein ECs (HUVECs), with a focus on the autophagy-mediated apoptotic pathway...

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Detalles Bibliográficos
Autores principales: Kim, Geun-Young, Jung, Inkyo, Park, Minhan, Park, Kihong, Lee, Seung Hee, Kim, Won-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529885/
https://www.ncbi.nlm.nih.gov/pubmed/36192481
http://dx.doi.org/10.1038/s41598-022-21044-3