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Multidimensional analysis of behavior predicts genotype with high accuracy in a mouse model of Angelman syndrome
Angelman syndrome (AS) is a neurodevelopmental disorder caused by loss of expression of the maternal copy of the UBE3A gene. Individuals with AS have a multifaceted behavioral phenotype consisting of deficits in motor function, epilepsy, cognitive impairment, sleep abnormalities, as well as other co...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529912/ https://www.ncbi.nlm.nih.gov/pubmed/36192373 http://dx.doi.org/10.1038/s41398-022-02206-3 |