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Multidimensional analysis of behavior predicts genotype with high accuracy in a mouse model of Angelman syndrome

Angelman syndrome (AS) is a neurodevelopmental disorder caused by loss of expression of the maternal copy of the UBE3A gene. Individuals with AS have a multifaceted behavioral phenotype consisting of deficits in motor function, epilepsy, cognitive impairment, sleep abnormalities, as well as other co...

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Detalles Bibliográficos
Autores principales: Tanas, Joseph K., Kerr, Devante D., Wang, Li, Rai, Anika, Wallaard, Ilse, Elgersma, Ype, Sidorov, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529912/
https://www.ncbi.nlm.nih.gov/pubmed/36192373
http://dx.doi.org/10.1038/s41398-022-02206-3