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Knowledge of the perturbation design is essential for accurate gene regulatory network inference

The gene regulatory network (GRN) of a cell executes genetic programs in response to environmental and internal cues. Two distinct classes of methods are used to infer regulatory interactions from gene expression: those that only use observed changes in gene expression, and those that use both the o...

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Detalles Bibliográficos
Autores principales: Seçilmiş, Deniz, Hillerton, Thomas, Tjärnberg, Andreas, Nelander, Sven, Nordling, Torbjörn E. M., Sonnhammer, Erik L. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529923/
https://www.ncbi.nlm.nih.gov/pubmed/36192495
http://dx.doi.org/10.1038/s41598-022-19005-x