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Activation of RhoC by regulatory ubiquitination is mediated by LNX1 and suppressed by LIS1

Regulation of Rho GTPases remains a topic of active investigation as they are essential participants in cell biology and the pathophysiology of many human diseases. Non-degrading ubiquitination (NDU) is a critical regulator of the Ras superfamily, but its relevance to Rho proteins remains unknown. W...

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Detalles Bibliográficos
Autores principales: Kholmanskikh, Stanislav, Singh, Shawn, Ross, M. Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529947/
https://www.ncbi.nlm.nih.gov/pubmed/36192543
http://dx.doi.org/10.1038/s41598-022-19740-1