Cargando…

UL49 is an essential subunit of the viral pre-initiation complex that regulates human cytomegalovirus gene transcription

More than half the world’s population is infected with human cytomegalovirus (HCMV), causing congenital birth defects and impacting the immuno-compromised. Many of the >170 HCMV genes remain uncharacterized, and this gap in knowledge limits the development of novel antivirals. In this study, we i...

Descripción completa

Detalles Bibliográficos
Autores principales: Turner, Declan L., Fritzlar, Svenja, Sadeghipour, Sara, Barugahare, Adele A., Russ, Brendan E., Turner, Stephen J., Mathias, Rommel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530030/
https://www.ncbi.nlm.nih.gov/pubmed/36204275
http://dx.doi.org/10.1016/j.isci.2022.105168